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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS15
All Species:
24.24
Human Site:
Y228
Identified Species:
53.33
UniProt:
P42566
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42566
NP_001153441.1
896
98656
Y228
S
P
A
E
K
A
K
Y
D
E
I
F
L
K
T
Chimpanzee
Pan troglodytes
XP_001139393
896
98643
Y228
S
P
A
E
K
A
K
Y
D
E
I
F
L
K
T
Rhesus Macaque
Macaca mulatta
XP_001113811
1015
110551
F384
P
V
A
D
K
M
R
F
D
E
I
F
L
K
T
Dog
Lupus familis
XP_532580
889
97932
Y215
S
P
A
E
K
A
K
Y
D
E
I
F
L
K
T
Cat
Felis silvestris
Mouse
Mus musculus
P42567
897
98453
Y228
S
P
A
E
K
A
K
Y
D
E
I
F
L
K
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026454
920
100691
Y263
S
P
A
D
K
I
K
Y
D
E
I
F
V
K
T
Frog
Xenopus laevis
O42287
1270
143652
Y224
P
S
S
S
R
L
K
Y
R
Q
L
F
N
S
Q
Zebra Danio
Brachydanio rerio
XP_002663145
1039
114340
Y262
S
P
A
D
K
A
K
Y
D
D
L
F
A
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122937
1043
116535
A267
S
S
E
D
Q
I
A
A
D
K
L
F
L
Q
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192039
1179
125310
C370
T
T
E
D
S
T
N
C
Y
I
L
F
K
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P34216
1381
150765
F281
S
F
E
K
K
Q
Q
F
D
A
I
F
D
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
43.2
91.5
N.A.
89.3
N.A.
N.A.
N.A.
74.6
21
50.5
N.A.
N.A.
30.1
N.A.
29.6
Protein Similarity:
100
99.7
59.5
94.5
N.A.
93.4
N.A.
N.A.
N.A.
84.1
34.9
64.4
N.A.
N.A.
48.2
N.A.
44.3
P-Site Identity:
100
100
60
100
N.A.
100
N.A.
N.A.
N.A.
80
20
73.3
N.A.
N.A.
26.6
N.A.
6.6
P-Site Similarity:
100
100
80
100
N.A.
100
N.A.
N.A.
N.A.
93.3
46.6
93.3
N.A.
N.A.
60
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
64
0
0
46
10
10
0
10
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
46
0
0
0
0
82
10
0
0
10
0
0
% D
% Glu:
0
0
28
37
0
0
0
0
0
55
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
19
0
0
0
100
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
19
0
0
0
10
64
0
0
0
0
% I
% Lys:
0
0
0
10
73
0
64
0
0
10
0
0
10
64
0
% K
% Leu:
0
0
0
0
0
10
0
0
0
0
37
0
55
0
19
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% N
% Pro:
19
55
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
10
10
0
0
10
0
0
0
19
10
% Q
% Arg:
0
0
0
0
10
0
10
0
10
0
0
0
0
0
0
% R
% Ser:
73
19
10
10
10
0
0
0
0
0
0
0
0
19
0
% S
% Thr:
10
10
0
0
0
10
0
0
0
0
0
0
0
0
64
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
64
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _